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K Park, D Lee, J Jeong, S Lee, S Kim, K Ahn. Human immunodeficiency virus-1 induces host genomic R-loop and preferentially integrates its genome near the R-loop regions. eLife. Reviewed preprint. 2024 Nov 11.
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GH Hwang, SH Lee, M Oh, O Habib, HK Jang, HS Kim, Y Kim, CH Kim, S Kim, S Bae. Large DNA deletions occur during DNA repair at 20-fold lower frequency for base editors and prime editors than for Cas9 nucleases. Nature Biomedical Engineering. 2024 Nov 04.
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Kim J, Koo B, Kim S. PONYTA: prioritization of phenotype-related genes from mouse KO events using PU learning on a biological network. Bioinformatics. 2024 Oct 21.
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Rafi AM, Nogina D, Penzar D, Lee D, Lee D, Kim N, Kim S, Kim D, Shin Y, Kwak I, Meshcheryakov G, Lando A, Zinkevich A, Kim BC, Lee J, Kang T, Vaishnav ED, Yadollahpour P, Random Promoter DREAM Challenge Consortium, Kim S, Albrecht J, Regev A, Gong W, Kulakovskiy IV, Meyer P, de Boer CG. A community effort to optimize sequence-based deep learning models of gene regulation. Nature Biotechnology. 2024 Oct 11.
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Cho C, Lee S, Bang D, Piao Y, Kim S. ChemAP: predicting drug approval with chemical structures before clinical trial phase by leveraging multi-modal embedding space and knowledge distillation. Scientific Reports. 2024 Oct 3.
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Yoon H, Lee D, Song S, Koo B, Park J, Kim TK, Kim S, Kim S, Hong J, Byun JM, Shin, D-Y, Kim I, Koh, Y, Yoon S-S. Unraveling the impact of lysosomal dysfunction on myeloproliferative neoplasm. Cancer Medicine. 2024 Sep 25.
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Pak M, Bang D, Sung I, Kim S, Lee S. DGDRP: Drug-specific Gene selection for Drug Response Prediction via re-ranking through propagating and learning biological network. Frontiers in Genetics. 2024 Sep 20
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SY Hwang, H Kim, D Denisko, B Zhao, D Lee, J Jeong, J Kim, K Park, J Park, D Jeong, S Park, HJ Choi, S Kim, EA Lee, K Ahn. Human cytomegalovirus harnesses host L1 retrotransposon for efficient replication. Nature Communications. 2024 Sep 02.
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Lee S, Park J, Piao Y, Lee D, Lee D, Kim S. Multi-layered Knowledge Graph Neural Network Reveals Pathway-level Agreement of Three Breast Cancer Multi-gene Assays. Computational and Structural Biotechnology Journal. 2024 Apr 22.
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Koh J, Jeong D, Park SY, Han D, Kim DS, Kim HY, Kim H, Yang S, Kim S, Ryu HS. Identification of VWA5A as a novel biomarker for inhibiting metastasis in breast cancer by machine-learning based protein prioritization. Scientific Reports. 2024 Jan 30.
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Park S, Lee S, Pak M, Kim S. Dual Representation Learning for Predicting Drug-side Effect Frequency using Protein Target Information. IEEE Journal of Biomedical and Health Informatics. 2024 Jan 5.
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Ha S, Kim J, Piao Y, Kim S. MV-CLAM: Multi-View Molecular Interpretation with Cross-Modal Projection via Language Model. NeurIPS 2024 AI for New Drug Modalities Workshop. 2024 Dec 15(Upcoming)
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Lu Y, Piao Y, Lee S, Kim S. Context-Aware Hierarchical Fusion for Drug Relational Learning. 23rd International Workshop on Data Mining in Bioinformatics (BIOKDD). 2024 Aug 26
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Lu Y, Lee S, Kang S, Kim S. Mixture-of-Experts Approach for Enhanced Drug-Target Interaction Prediction and Confidence Assessment. 23rd International Workshop on Data Mining in Bioinformatics (BIOKDD). 2024 Aug 26
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Bang D, Koo B, Kim S. Transfer Learning of Condition-Specific Perturbation in Gene Interactions Improves Drug Response Prediction. Bioinformatics, 2024 Jul. [From The 32nd Intelligent Systems for Molecular Biology (ISMB)]
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Piao Y, Lee S, Lu Y, Kim S. Improving Out-of-Distribution Generalization in Graphs via Hierarchical Semantic Environments. CVPR 2024. 2024 Mar
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Lee D, Lee D, Bang D, Kim S. DiSCO: Diffusion Schrödinger Bridge for Molecular Conformer Optimization. AAAI 2024. 2024
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Lu Y, Piao Y, Kim S. Enhancing Drug-Drug Interaction Prediction with Context-Aware Architecture. ICLR 2024 Tiny Paper Track. 2024 Feb 16
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Jeong D, Koo B, Oh M, Kim TB, Kim S. GOAT: Gene-level biomarker discovery from multi-Omics data using graph ATtention neural network for eosinophilic asthma subtype. Bioinformatics. 2023 Sep 22.
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Yi J, Lee S, Lim S, Cho C, Piao Y, Yeo M, Kim D, Kim S, Lee S. Exploring chemical space for lead identification by propagating on chemical similarity network. Computational and Structural Biotechnology Journal. 2023 Aug 25.
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Gu J, Bang D, Yi J, Lee S, Kim DK, Kim S. A model-agnostic framework to enhance knowledge graph-based drug combination prediction with drug–drug interaction data and supervised contrastive learning. Briefings in Bioinformatics. 2023 Aug 7.
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Jeon H, Ahn J, Na B, Hong S, Lee S, Kim S, Yoon S, Baek D. AIVariant: a deep learning-based somatic variant detector for highly contaminated tumor samples. Experimental & Molecular Medicine. 2023 Aug 1.
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Yoon JK, Park S, Lee KH, Jeong D, Woo J, Park J, Yi SM, Han D, Yoo CG, Kim S, Lee CH. Machine Learning-Based Proteomics Reveals Ferroptosis in COPD Patient-Derived Airway Epithelial Cells Upon Smoking Exposure. Journal of Korean Medical Science. 2023 July 24.
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Bang D, Lim S, Lee S, Kim S. Biomedical knowledge graph learning for drug repurposing by extending guilt-by-association to multiple layers. Nature Communications. 2023 June 15.
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AM Rafi, D Penzar, D Nogina, D Lee, ED Vaishnav, D Lee, N Kim, S Kim, G Meshcheryakov, A Lando, P Yadollahpour, A Zinkevich, D Kim, Y Shin, IY Kwak, BC Kim, J Lee, Random Promoter DREAM Challenge Consortium, S Kim, A Regev, J Albrecht, W Gong, IV Kulakovskiy, P Meyer & CG de Boer. Evaluation and optimization of sequence-based gene regulatory deep learning models. bioRxiv. 2023 Apr 28.
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C Cho, D Lee, D Jeong, S Kim, MK Kim & S Srinivasan. Characterization of radiation-resistance mechanism in Spirosoma montaniterrae DY10T in terms of transcriptional regulatory system. Scientific Reports 13.1 (2023): 4739. 2023 Mar 23.
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Lee D, Koo B, Yang J, Kim S. Metheor: Ultrafast DNA methylation heterogeneity calculation from bisulfite read alignments. PLOS Computational Biology. 2023 Mar 20.
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Lee D, Koo B, Kim S, Byun J, Hong J, Shin D, Sun C, Song J, Kim J, Jaiswal S, Yoon S, Kim S, Koh Y. AMLs harboring DNMT3A-destabilizing variants show increased intratumor DNA methylation heterogeneity at bivalent chromatin domains. bioRxiv. 2023 Feb 14.
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Pak M, Lee S, Sung I, Koo B, Kim S. Improved drug response prediction by drug target data integration via network-based profiling. Briefings in Bioinformatics. 2023 Feb 8.
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Lim S, Kim Y, Gu J, Lee S, Shin W, Kim S. Supervised chemical graph mining improves drug-induced liver injury prediction. iScience. 2023 Jan 20.
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Kwon Y, Lee D, Kim JW, Choi YS, Kim S. Exploring Optimal Reaction Conditions Guided by Graph Neural Networks and Bayesian Optimization. ACS Omega. 2022 Dec 2.
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Kwon Y, Kim S, Choi YS, Kang S. Generative Modeling to Predict Multiple Suitable Conditions for Chemical Reactions. Journal of Chemical Information and Modeling (JCIM). 2022 Nov 22.
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Shin J, Piao Y, Bang D, Kim S, Jo K. DRPreter: Interpretable Anticancer Drug Response Prediction Using Knowledge-Guided Graph Neural Networks and Transformer. International Journal of Molecular Sciences (IJMS). 2022 Nov 11.
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Lee D, Yang J, Kim S. Learning the histone codes with large genomic windows and three-dimensional chromatin interactions using transformer. Nature Communications. 2022 Nov 5.
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Choi B, Kang CK, Park S, Lee D, Lee AJ, Ko Y, Kang SJ, Kang K, Koh Y, Jung I. Single-cell transcriptome analyses reveal distinct gene expression signatures of severe COVID-19 in the presence of clonal hematopoiesis. Experimental & Molecular Medicine (EMM). 2022 Oct 13.
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Bang D, Gu J, Park J, Jeong D, Koo B, Yi J, Shin J, Jung I, Kim S, Lee S. A Survey on Computational Methods for Investigation on ncRNA-Disease Association through the Mode of Action Perspective. International Journal of Molecular Sciences (IJMS). 2022 Sep 29.
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Lim S, Lee S, Piao Y, Choi MG, Bang D, Gu J, Kim S. On Modeling and Utilizing Chemical Compound Information with Deep Learning Technologies: A Task-oriented Approach. Computational and Structural Biotechnology Journal (CSBJ). 2022 Aug 4.
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Park J, Lee D, Ham S, Oh J, Noh JR, Lee YK, Park YJ, Lee G, Han SM, Han JS, Kim YY, Jeon YG, Nahmgoong H, Shin KC, Kim SM, Choi SH, Lee CH, Park J, Roh TY, Kim S, Kim JB. Targeted erasure of DNA methylation by TET3 drives adipogenic reprogramming and differentiation. Nature Metabolism. 2022 July 4.
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Kim YY, Jang H, Lee G, Jeon YG, Sohn JH, Han JS, Lee WT, Park J, Huh JY, Nahmgoong H, Han SM, Kim J, Pak M, Kim S, Kim JS, Kim JB. Hepatic GSK3β-Dependent CRY1 Degradation Contributes to Diabetic Hyperglycemia. Diabetes. 2022 July 1.
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Han JS, Jeon YG, Oh M, Lee G, Nahmgoong H, Han SM, Kim YY, Shin KC, Kim J, Jo K, Choe SS, Park EJ, Kim S, Kim JB. Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes. Nat Commun., 2022 June .
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Lee G, Kim YY, Jang H, Han JS, Nahn N, Park YJ, Han SM, Cho C, Lim S, Noh JR, Oh WK, Lee CH, Kim S, Kim JB. SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity. Cell Metabolism. 2022 May 3.
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Sung I, Lee S, Pak M, Shin Y, Kim S. AutoCoV: tracking the early spread of COVID-19 in terms of the spatial and temporal patterns from embedding space by K-mer based deep learning. BMC Bioinformatics. 2022 Apr 25.
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Pak M, Lee S, Sung I, Shin Y, Jung I, Kim S. COVID-19 Virus Whole-genome Embedding Strategy through Density-based Clustering and Deep Learning Model. JOK. 2022 Apr.
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Kim M, Lee S, Lim S, Lee DY, Kim S. Subnetwork Representation Learning for Discovering Network Biomarkers in Predicting Lymph Node Metastasis in Early Oral Cancer. Scientific Reports 11 (23992), 1-12. 2021 Dec 14.
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Lee D, Kim S. Knowledge-guided artificial intelligence technologies for decoding complex multiomics interactions in cells. Clinical and Experimental Pediatrics. 2021 Nov 26. Online ahead of print.
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Sohn JH, Ji Y, Cho CY, Nahmgoong H, Lim S, Jeon YG, Han SM, Han JS, Park I, Rhee HW, Kim S, Kim JB. Spatial Regulation of Reactive Oxygen Species via G6PD in Brown Adipocytes Supports Thermogenic Function. Diabetes. 2021 Sep 14.
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Jung I, Kim M, Rhee S, Lim S, Kim S. MONTI: A Multi-Omics Non-negative Tensor Decomposition Framework for Gene-Level Integrative Analysis. Frontiers in Genetics, 2021 Sep 10.
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Park S, Lee D, Kim Y, Lim S, Chae H, Kim S. BioVLAB-Cancer-Pharmacogenomics: Tumor Heterogeneity and Pharmacogenomics Analysis of Multi-omics Data from Tumor on the Cloud. Bioinformatics. 2021 June 29.
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Jo K, Sung I, Lee D, Jang H, Kim S. Inferring transcriptomic cell states and transitions only from time series transcriptome data. Scientific Reports 11 (1), 1-13. 2021 June 15.
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Lee T, Lee S, Kang M, Kim S. Deep hierarchical embedding for simultaneous modeling of GPCR proteins in a unified metric space. Scientific Reports 11 (1) 1-11. 2021 May 05.
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Jeong D, Lim S, Lee S, Oh M, Cho C, Seong H, Jung W, Kim S. Construction of Condition-Specific Gene Regulatory Network using Kernel Canonical Correlation Analysis. Frontiers in Genetics. 2021 Mar 26.
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Moon JH, Lee S, Pak M, Hur B, Kim S. MLDEG: A Machine Learning Approach to Identify Differentially Expressed Genes Using Network Property and Network Propagation. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 2021 Mar 22.
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Park YJ, Lee S, Lim S, Hahn N, Ji Y, Huh JY, Alfadda AA, Kim S, Kim JB. DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics. Proceedings of the National Academy of Sciences (PNAS). 2021 Mar 16.
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Lim S, Lu Y, Cho CY, Sung I, Kim J, Kim Y, Park S, Kim S. A Review on Compound-Protein Interaction Prediction Methods: Data, Format, Representation and Model. Computational and Structural Biotechnology Journal (CSBJ). 2021 Mar 10.
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Lee HB, Lee SB, Kim M, Kwon S, Jo J, Kim J, Lee HJ, Ryu HS, Lee JW, Kim C, Jeong J, Kim H, Noh DY, Park IA, Ahn SH, Kim S, Yoon S, Kim A, Han W. Development and Validation of a Next-Generation Sequencing-Based Multigene Assay to Predict the Prognosis of Estrogen Receptor-Positive, HER2-Negative Breast Cancer. Clinical Cancer Research 26 (24), 6513-6522. 2020 Dec 15.
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Oh M, Park S, Lee S, Lee D, Lim S, Jeong D, Jo K, Jung I, Kim S. DRIM: A web-based system for investigating drug response at the molecular level by condition-specific multi-omics data integration. Frontiers in Genetics. 2020 Nov 12.
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Jo HY, Lee Y, Ahn H, Han HJ, Kwon A, Kim BY, Ha HY, Kim SC, Kim JH, Kim YO, Kim S, Koo SK, Park MH. Functional in vivo and in vitro effects of 20q11.21 genetic aberrations on hPSC differentiation. Scientific reports 10 (1), 1-14. 2020 Oct 29.
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Min A, Kim K, Jeong K, Choi S, Kim SY, Suh K-J, Lee K-H, Kim S, Im S-A. Homologous Repair Deficiency score for identifying breast cancers with defective DNA damage response beyond BBCA mutations. Scientific Reports, 10(1):1-14, 2020 Jul 27.
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Kang M, Lee S, Lee D, Kim S. Learning Cell-Type-Specific Gene Regulation Mechanisms by Multi-Attention Based Deep Learning with Regulatory Latent Space. Frontiers in Genetics, 2020 Sep 30.
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Lee D, Park Y, Kim S. Towards multi-omics characterization of tumor heterogeneity: a comprehensive review of statistical and machine learning approaches. Briefings in Bioinformatics, 2020 Aug 25.
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Jo K, Santos-Buitrago B, Kim M, Rhee S, Talcott C, Kim S. Logic-based analysis of gene expression data predicts association between TNF, TGFB1 and EGF pathways in basal-like breast cancer. Methods, 2020 July 1.
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Hoang N. V., Choe G, Zheng Y, Fandino A. C. A, Sung I, Hur J, Kamran M, Park C, Kim H, Ahn H, Kim S, Fei Z, Lee J. Identification of Conserved Gene-Regulatory Networks that Integrate Environmental Sensing and Growth in the Root Cambium. Current Biology, 2020 Aug 3.
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Oh M, Park S, Kim S, Chae H. Machine learning-based analysis of multi-omics data on the cloud for investigating gene regulations. Briefings in Bioinformatics, 2020 Mar 30.
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Lee S, Lim S, Lee T, Sung I, Kim S. Cancer subtype classification and modeling by pathway attention and propagation. Bioinformatics, 2020 Mar 24.
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Jo HY, Han HW, Jung I, Ju JH, Park SJ, Moon S, Geum D, Kim H, Park HJ, Kim S, Stacey G.N., Koo SK, Park MH. Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives. Scientific Reports, 2020 Mar 3.
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Lee CJ, Ahn H, Jeong D, Pak M, Moon JH, Kim S. Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer. BMC Medical Genomics, 2020 Feb 24. [From The 30th International Conference on Genome Informatics (GIW)]
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Hur B, Kang D, Lee S, Moon JH, Lee G, Kim S. Venn-diaNet: Venn diagram based network propagation analysis framework for computing multiple biological experiments. BMC Bioinformatics, 2019 Dec 27. [From The 30th International Conference on Genome Informatics (GIW)]
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Kang D, Ahn H, Lee S, Lee CJ, Hur J, Jung W, Kim S. StressGenePred: a twin prediction model architecture for classifying the stress types of samples and discovering stress-related genes in Arabidopsis. BMC Genomics, 2019 Dec 20.
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Kim HJ, Moon JH, Shin JS, Kim B, Kim JS, Yoon IH, Min BH, Kim JM, Kang SJ, Kim YH, Jo K, Choi J, Chae H, Lee WW, Kim S, Park CG. Bioinformatics analyses with peripheral blood RNA-sequencing unveiled the cause of the graft loss after pig-to-nonhuman primate islet xenotransplantation model. Scientific Reports. 2019 Dec 11
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Ahn H, Jung I, Chae H, Kang D, Jung W, Kim S. HTRgene: a computational method to perform the integrated analysis of multiple heterogeneous time-series data: case analysis of cold and heat stress response signaling genes in Arabidopsis. BMC Bioinformatics, 2019 Dec 2.
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Kim M, Lee S, Lim S, Kim S. SpliceHetero: An information theoretic approach for measuring spliceomic intratumor heterogeneity from bulk tumor RNA-seq. PloS ONE. 2019 Oct 23.
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Lee S, Lee T, Noh YK, Kim S. Ranked k-spectrum kernel for comparative and evolutionary comparison of exons, introns, and CpG islands. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2019 Sep 3.
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Lim A, Lim S, Kim S. Enhancer Prediction with Histone Modification Marks Using a Hybrid Neural Network Model. Methods, 2019 Aug 15.
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Kim JI, Park J, Ji Y, Jo K, Han SM, Sohn JH, Shin KC, Han JS, Jeon YG, Goong HN, Han KH, Kim J, Kim S, Choe SS, Kim JB. During adipocyte remodeling, lipid droplet configurations regulate insulin sensitivity through F/G-actin reorganization. Molecular and Cellular Biology, 2019 Jul 20
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Lee D, Lee S, Kim S. PRISM: Methylation Pattern-based, Reference-free Inference of Subclonal Makeup. Bioinformatics, 2019 Jul 5. [From The 27th Intelligent Systems for Molecular Biology (ISMB)]
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Jang Y, Seo J, Jang I, Lee B, Kim S, Lee S. CaPSSA: visual evaluation of cancer biomarker genes for patient stratification and survival analysis using mutation and expression data. Bioinformatics, 2019 Jun 22
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Kim S, Kang JW, Yoon S. Cracking the code of personalized medicine. Nature Research 2019 (advertisement article).
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Ahn H, Jo K, Jeong D, Pak M, Hur J, Jung W, Kim S. PropaNet: Time-varying condition-specific transcriptional network construction by network propagation. Frontiers in Plant Science, 2019 Jun 14.
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Hwang I, Jo K, Shin KC, Kim JI, Ji Y, Park YJ, Park J, Jeon YG, Ka S, Suk S, Noh HL, Choe SS, Alfadda AA, Kim JK, Kim S, Kim JB. GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity. Proceedings of the National Academy of Sciences (PNAS), 2019 Jun 3.
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Kang H, Ahn H, Jo K, Oh M, Kim S. mirTime: Identifying Condition-Specific Targets of MicroRNA in Time-series Transcript Data using Gaussian Process Model and Spherical Vector Clustering. Bioinformatics. 2019 May 9.
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Park S, Kim M, Seo S, Hong S, Han K, Lee K, Cheon JH, Kim S. A secure SNP panel scheme using homomorphically encrypted K-mers without SNP calling on the user side. BMC Genomics, 2019 Apr 4. [From The 17th Asia Pacific Bioinformatics Conference (APBC)]
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Choi J, Park Y, Kim S, Chae H. CloudBS: A MapReducebased bisulfite sequencing aligner on cloud. Journal of Bioinformatics and Computational Biology. 2018 Dec 19.
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Seo S, Park Y, Chae H. BiSpark: a Spark-based highly scalable aligner for bisulfite sequencing data. BMC Bioinformatics. 2018 Dec 10.
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Lim S, Lee S, Jung I, Rhee S, Kim S. Comprehensive and critical evaluation of individualized pathway activity measurement tools on pan-cancer data. Briefings in Bioinformatics. 2018 Nov 20.
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Seo S, Oh M, Park Y, Kim S. DeepFam: Deep learning based alignment-free method for protein family modeling and prediction. Bioinformatics, 2018 Jul 1. [From The 26th Intelligent Systems for Molecular Biology (ISMB)]
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Lee CJ, Kang D, Lee S, Lee S, Kang J, Kim S. In silico experiment system for testing hypothesis on gene functions using three condition specific biological networks. Methods. 2018 May 11.
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Jung I, Kang H, K JU, Chang H, Kim S, Jung W. The mRNA and miRNA transcriptomic landscape of Panax ginseng under the high ambient temperature. BMC Systems Biology. 2018 Mar 19.
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Kim I, Choi S, Kim S, BRCA-Pathway: a structural integration and visualization system of TCGA breast cancer data on KEGG pathways. BMC Bioinformatics. 2018 Feb 19.
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L'Yi S, Jung D, Oh M, Kim B, Freishtat RJ, Giri M, Hoffman E, Seo J. miRTarVis+: Web-based interactive visual analytics tool for microRNA target predictions. Methods. 2017 Jul 15.
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Ahn H, Jung I, Shin SJ, Park J, Rhee S, Kim JK, Jung W, Kwon HB, Kim S. Transcriptional Network Analysis Reveals Drought Resistance Mechanisms of AP2/ERF Transgenic Rice. Frontiers in Plant Science. 2017 Jun 15.
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Lee S, Park Y, Kim S. MIDAS: Mining differentially activated subpaths of KEGG pathways from multi-class RNA-seq data. Methods. 2017 Jun 1.
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Oh M, Rhee S, Moon JH, Chae H, Lee S, Kang J, Kim S, Literature-based condition-specific miRNA-mRNA target prediction. PLoS ONE. 2017 Mar 31.
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Rhee S, Lim S, Kim S, Iterative segmented least square method for functional microRNA-mRNA module discovery in breast cancer. International Journal of Data Mining and Bioinformatics. 2017 Jan.
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Moon JH, Lim S, Jo K, Lee S, Seo S, Kim S, PINTnet: construction of condition-specic pathway interaction network by computing shortest paths on weighted PPI. BMC Systems Biology. 2017 Mar 14.
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Jung I, Jo K, Kang H, Ahn H, Yu Y, Kim S, TimesVector: a vectorized clustering approach to the analysis of time series transcriptome data from multiple phenotypes. Bioinformatics. 2017 Dec 1.
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Shin SJ, Ahn H, Jung I, Rhee S, Kim S, Kwon HB, Novel drought-responsive regulatory coding and non-coding transcripts from Oryza Sativa L. Genes & Genomics. 2016 Jun 9.
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Chae H, Lee S, Nephew KP, Kim S, Subtype-specific CpG island shore methylation and mutation patterns in 30 breast cancer cell lines. BMC Systems Biology, 2016 Dec 23.
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Jung I, Ahn H, Shin SJ, Kim J, Kwon HB, Jung W, Kim S. Clustering and evolutionary analysis of small RNAs identify regulatory siRNA clusters induced under drought stress in rice. BMC Systems Biology, 2016 Dec 23.
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Lee J, Jo K, Lee S, Kang J, Kim S. Prioritizing biological pathways by recognizing context in time-series gene expression data. BMC Bioinformatics, 2016 Dec 23.
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Park Y, Lim S, Nam J, Kim S. Measuring intratumor heterogeneity by network entropy using RNA-seq data, Scientific Reports, 2016 Nov 24.
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Hur B, Lim S, Chae H, Seo S, Lee S, Kang J, Kim S. CLIP-GENE: a web service of the condition specific context-laid integrative analysis for gene prioritization in mouse TF knockout experiments. Biology Direct, 2016 Nov 1.
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Lim S, Park Y, Hur B, Kim M, Han W, Kim S. Protein interaction network (PIN)-based breast cancer subsystem identification and activation measurement for prognostic modeling. Methods. 2016 Nov 1.
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Park J, Hur B, Rhee S, Lim S, Kim M, Kim K, Han W, Kim S. Information theoretic sub-network mining characterizes breast cancer subtypes in terms of cancer core mechanisms. Journal of Bioinformatics and Computational Biology. 2016 Oct 7.
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Lee CJ, Ahn H, Lee SB, Shin J, Park WY, Kim JI, Lee J, Ryu H, Kim S, Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice. BMC Medical Genomics. 2016 Aug 12.
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Chae H, Lee S, Seo S, Jung D, Chang H, Nephew KP, Kim S. BioVLAB-mCpG-SNP-EXPRESS: A system for multi-level and multi-perspective analysis and exploration of DNA methylation, sequence variation (SNPs), and gene expression from multi-omics data. Methods. 2016 Jul 28.
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Jeong HM, Lee S, Chae H, Kim R, Kwon MJ, Oh E, Choi YL, Kim S, Shin YK. Efficiency of methylated DNA immunoprecipitation bisulphite sequencing for whole-genome DNA methylation analysis. Epigenomics. 2016 Jun 8.
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Jang Y, Yu N, Seo J, Kim S, Lee S, MONGKIE: an integrated tool for network analysis and visualization for multi-omics data. Biology Direct. 2016 Mar 18.
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Jo K, Jung IU, Moon JH, Kim S, Influence maximization in time bounded network identifies transcription factors regulating perturbed pathways. Bioinformatics. 2016 Jun 15.
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Kim M, Hur B, Kim S. RDDpred: a condition-specific RNA-editing prediction model from RNA-seq data. BMC Genomics. 2016 Jan 11.
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Hur B, Chae HJ, Kim S. Combined analysis of gene regulatory network and SNP information enhances identification of potential gene markers in mouse knockout studies with small number of samples. BMC Medical Genomics. 2015 8(Suppl 2): S10.
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Sandhan T, Yoo YJ, Choi JY, Kim S., Graph Pyramid Approach for Protein Classification. BMC Medical Genomics. 2015 8(Suppl 2):S12.
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Kim Y, Kang YS, Lee NY, Kim KY, Hwang YJ, Kim HW, Rhyu IJ, Her S, Jung MK, Kim S, Lee CJ, Ko S, Kowall NW, Lee SB, Lee J, Ryu H, Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency., Autophagy, 2015 May 5
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Yerrapragada S, Shukla A, Hallsworth-Pepin K, Choi K, Wollam A, Clifton S, Qin X, Muzny D, Raghuraman S, Ashki H, Uzman A, Highlander SK, Fryszczyn BG, Fox GE, Tirumalai MR, Liu Y, Kim S, Kehoe DM, Weinstock GM., Extreme Sensory Complexity Encoded in the 10-Megabase Draft Genome Sequence of the Chromatically Acclimating Cyanobacterium Tolypothrix sp. PCC 7601.Genome Announc. 2015 May 7;3(3)
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Rhee S, Chae H, Kim S. PlantMirnaT: miRNA and mRNA integrated analysis fully utilizing characteristics of plant sequencing data. Methods. 2015 Jul 15;83:80-7.
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Kim KY, Hwang YJ, Jung MK, Choe J, Kim Y, Kim S, Lee CJ, Ahn H, Lee J, Kowall NW, Kim YK, Kim JI, Lee SB, Ryu H. A multifunctional protein EWS regulates the expression of Drosha and microRNAs. Cell Death Differ. 2013 Nov 1. doi: 10.1038/cdd.2013.144.
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Rhee J, Kim K, Chae H, Evans J, Yan P, Zhang B, Gray J, Spellman P, Huang T, Nephew K and Kim S. Integrated Analysis of Genome-wide DNA Methylation and Gene Expression Profiles in Molecular Subtypes of Breast Cancer, Nucleic Acids Res. 2013 July 2;41(18):8464-8474.doi: 10.1093/nar/gkt643
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Rhee SM, Park JW, and Kim S. Computational regulatory network construction from microRNA and transcription factor perspectives. ACM SIG Bio Record, Volume 3, Issue 3, May 2013 ISSN 2159-1210.
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Lee KY and Kim S, Designing Discriminative Spatial Filter Vectors in Motor Imagery Brain–Computer Interface, International Journal of Imaging Systems and Technology, Vol. 23, No. 2, 2013, 147–151.
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Chae HJ, Park, JW, Lee SW, Nephew KP, Kim S. Comparative Analysis Using K-mer and K-flank Patterns Provides Evidence for CpG Island Sequence Evolution in Mammalian Genomes, Nucleic Acids Res. 2013 May 1;41(9):4783-91.
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An JH, Kim KS, Rhee SM, Chae HJ, Nephew KP, Kim S. Genome-wide analysis and modeling of DNA methylation susceptibility in 30 breast cancer cell lines by using CpG flanking sequences. Journal of Bioinformatics and Computational Biology. 2013 Jun;11(3):1341003. doi: 10.1142/S0219720013410035.
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Chae H, Jung I, Lee H, Marru S, Lee SW and Kim S. Bio and Health informatics meets Cloud : BioVLab as an example. Health Information Science and Systems 2013, 1:6
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Nam S, Long X, Kwon C, Kim S, Nephew KP. An integrative analysis of cellular contexts, miRNAs and mRNAs reveals network clusters associated with antiestrogen-resistant breast cancer cells. BMC Genomics. 2012 Dec 27;13:732.
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Rao X, Evans J, Chae H, Pilrose J, Kim S, Yan P, Huang RL, Lai HC, Lin H, Liu Y, Miller D, Rhee JK, Huang YW, Gu F, Gray JW, Huang TM, Nephew KP. CpG island shore methylation regulates caveolin-1 expression in breast cancer. Oncogene, 2012 Nov 5. doi: 10.1038/onc.2012.474.
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Lee H, Yang Y, Chae H, Nam S, Choi D, Tangchaisin P, Herath C, Marru S, Nephew K, Kim S. BioVLAB-MMIA: A Cloud Environment for microRNA andmRNA Integrated Analysis (MMIA) on Amazon EC2, IEEE Transactions on NanoBioscience, Volume 11, Issue 3, Sept. 2012 ISSN 1536-1241. doi:10.1109/TNB.2012.2212030
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Pejaver VR, An J, Rhee SM, Bhan A, Choi JH, Liu B, Lee H, Brown PJ, Kysela D, Brun YV, Kim S. GeneclusterViz: a tool for conserved gene cluster visualization, exploration and analysis, Bioinformatics, 2012, 28(11), 1527-1529.
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Gupta R, Kim S, Taylor MW. Suppression of ribosomal protein synthesis and protein translation factors by Peg-interferon alpha/ribavirin in HCV patients blood mononuclear cells (PBMC), Journal of Translational Medicince, 2012 10:54.
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Yang Y, Nephew NP, Kim S. A Novel K-mer Mixture Logistic Regression for Methylation Susceptibility Modeling of CpG Dinucleotides in Human Gene Promoters, BMC Bioinformatics, 2012, 13(suppl 3) S15.
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Lu YK, Marden J, Han M, Swingley WD, Mastrian SD, Chowdhury SR, Hao J, Helmy T, Kim S, Kurdoglu AA, Matthies HJ, Rollo D, Stothard P, Blankenship RE, Bauer CE, Touchman JW. Metabolic flexibility revealed in the genome of the cyst-forming alpha-1 proteobacterium Rhodospirillum centenum. BMC Genomics. 2010 May 25;11:325.
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Kim S. Data mining for the study of disease genes and proteins, Artif Intell Med. (editorial) 2010 Jul;49(3):133-4.
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Choi JH, Li Y, Guo J, Kramer R, Rauch T, Macmil S, Wiley G, Bennett L, Schnabel J, Taylor K, Kim S, Dong X, Sreekumar A, Pfeifer G, Roe B, Caldwell C, Bhalla H, Shi H. Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing, PLoS ONE, 2010 Sep 29;5(9)
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Rho M, Schaack S, Gao X, Kim S, Lynch M, Tang H. LTR retroelements in the genome of Daphnia pulex, BMC Genomics, 2010 Jul 9;11:425.
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Yang Y, Gibert D., Kim S. Confidence Score for Genome Annotation: A Genome Comparison Approach Bioinformatics, 26:22-29, 2010
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Li M, Balch C, Montgomery JS, Jeong MK, Chung JH, Yan P, Huang T H-M, Kim S, Nephew KP. Integrated Analysis of DNA Methylation and Gene Expression Reveals Specific Signaling Pathways Associated with Platinum Resistance in Ovarian Cancer BMC Medical Genomics, 2009, 2:34
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Rho M, Zhou M, Gao X, Kim S, Tang H, Lynch M. Independent Mammalian Genome Contractions Following the KT Boundary. Genome Biology and Evolution 2009:2
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Nam S, Li M, Choi K, Balch C, Kim S, Nephew KP. MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression. Nucleic Acids Res. 2009 May 6.
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Xin F, Li M, Balch C, Thomson M, Fan M, Liu Y, Hammond SM, Kim S, Nephew KP. Computational Analysis of MicroRNA Profiles and Their Target Genes Suggests Significant Involvement in Breast Cancer Antiestrogen Resistance. Bioinformatics. 2009 Feb 15;25(4):430-4.
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Tsukahara T, Kim S, Taylor MW. REFINEMENT: a search framework for the identification of interferon-responsive elements in DNA sequences--a case study with ISRE and GAS. Comput Biol Chem. 2006 Apr;30(2):134-47.
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Wei SH, Balch C, Paik HH, Kim YS, Baldwin RL, Liyanarachchi S, Li L,Wang Z. Wan JC, Davuluri RV, Karlan BY, Gifford G, Brown R, Kim S, Huang TH, Nephew KP. Prognostic DNA methylation biomarkers in ovarian cancer. Clin Cancer Res. 2006 May 1;12(9):2788-94.
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Li L, Cheng AS, Jin VX, Paik HH, Fan M, Li X, Zhang W, Robarge J, Balch C, Davuluri RV, Kim S, Huang TH, Nephew KP. A mixture model-based discriminate analysis for identifying ordered transcription factor binding site pairs in gene promoters directly regulated by estrogen receptor-alpha. Bioinformatics. 2006 Sep 15;22(18):2210-6.
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Song B, Choi JH, Chen G, Szymanski J, Zhang GQ, Tung AK, Kang J, Kim S, Yang J. ARCS: an aggregated related column scoring scheme for aligned sequences. Bioinformatics. 2006 Oct 1;22(19):2326-32.
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Kim S, Choi JH, Saple A, Yang J. A hybrid gene team model and its application to genome analysis. J Bioinform Comput Biol. 2006 Apr;4(2):171-96.
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Kim S, Lee J. BAG: a graph theoretic sequence clustering algorithm. Int J Data Min Bioinform. 2006;1(2):178-200.
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Lee D, Choi JH, Dalkilic MM, Kim S. COMPAM :visualization of combining pairwise alignments for multiple genomes. Bioinformatics. 2006 Jan 15;22(2):242-4.
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Lee CJ, Ahn H, Lee SB, Shin JY, Park WY, Kim JI, Lee JH, Ryu H, Kim S. Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of EWS KO mice. The 5th Translational Bioinformatics Conference (TBC 2015), Tokyo, Japan.
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Kim HJ, Moon JH, Shin JS, Kim BG, Kim JS, Min BH, Jo K, Kang SJ, Byun N, Phuong T, Kim JM, Kim S, Park CG. A new bioinformatics analysis can reveal intestinal infection as a cause of graft rejection in islet xenotransplantation in non-human primate. Presented at the Annual Meeting, American Association of Immunologist, May 2015, New Orleans, LA
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Kim HJ, Moon JH, Shin JS, Kim JS, Min BH, Kim JM, Kim YH, Lee WW, Kang BC, Kang SJ, Kim SJ, Jo K, Kim S, Park CG. A new bioinformatics analysis reveals intestinal infection as a possible cause of intrahepatic graft rejection in non-human primate porcine islet xenotransplantation. IPITA-IXA-CTS 2015, Nov 15-19, Melbourne, Australia
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Choi JY, Yang Y, Kim S, and Gannon D. VLAB-Proteins: a Collaborative Virtul Lab for Protein Sequence Anlaysis. Proc IEEE Workshop on High-Throughput Data Analysis for Proteomics and Genomics, pp 183-190, November 2-5, 2007, San Jose, CA
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Choi K, Yang Y, and Kim S. CLASSEQ: Classification of Multiple Sequences via Comparative Analysis of Multiple Genomes. Proc International Workshop on Machine Learning in Biomedicine and Bioinformatics (MLBB) with The Sixth International Conference on Machine Learning and Applications (ICMLA), pp 554-559, December 13-15, 2007
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Patwardhan R, Tang H, Kim S, and Dalkilic M. An approximate de Bruijn graph approach to multiple local alignment and motif discovery in protein sequences. Lecture Note in Bioinformatics 4316, Springer 2007
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Bhan A, Maryada BK, Choi K, and Brun Y, Kim S. EGGS: Extraction of Gene clusters by iteratively using Genome context based Sequence matching techniques. Proc IEEE International Conference on Bioinformatics and Biomedicine (BIBM), pp 23-28 November 2-5, 2007, San Jose, CA